Posts Tagged ‘health’

International Cannabis & Hemp Expo Coming To Oakland!

International Cannabis & Hemp Expo 3International Cannabis & Hemp Expo 3

CANNABIS EXPO INNOVATOR “TAKING IT TO THE STREETS”

OF OAKLAND PRESENTING LANDMARK EVENT

Saturday & Sunday, September 3rd and 4th

Oakland, Ca. – Cannabis activist and CEO of the International Cannabis & Hemp Expo (INTCHE) Kim Cue is proud to announce that the 2011 expo will be held out in the open on the streets of downtown Oakland on Saturday and Sunday, September 3rd and 4th from 12pm-8pm.  The area between 14th St., Clay St. and San Pablo Ave including Ogawa Park will be blocked off for this celebration of education, awareness, and advancement of the cannabis movement.  Located directly in front of City Hall will be the designated  “215 Area” for patients to medicate. INTCHE was the first event to have an approved onsite medicating area for patients, and it was the first to bring the cannabis community together with the hemp industry to educate the general public on the 2 related plants and their individual benefits to the populace.  Since the debut of the first INTCHE, many other producers have created events to try to capitalize on the emerging industry – but without a solid agenda of professionalism, education and advancement of the political movement for patients of medical cannabis.

The agenda for the 2-day event includes speaker’s panels debating current cannabis and hemp issues.  One of those will be a discussion of the upcoming 2012 initiative to put legalization on the ballot in California.  This topic holds significance because Colorado and Washington State have already put plans in motion to put it on the 2012 ballot as well.  Historically initiatives have a greater chance of passing in presidential election years and when they have 60% support going into the race.  Colorado is already at 80% approval.   Passage of legalization propositions in any or all of these states will force a showdown with the Feds over States’ rights.  The Gallup National Poll in October of 2010 showed 46% of Americans now would vote for full legalization, and that number continues to grow.

In addition to the panels there will be over 300 vendors with information about how to obtain a recommendation for medical use, new products, growing techniques, locations of dispensaries, etc.  There will be live entertainment and a complimentary hash bar in the 215 Area.  A variety of food and nonalcoholic beverages will be available at the event.  Surrounding restaurants and bars outside the event will be open for business.

Judges who have purchased the $300 VIP ticket will receive a SWAG Bag with over 320 samples the week prior to the event.  This will include 120 strains of cannabis, 40 hashes, 40 oils, 40 waxes, and a variety of edibles.  The VIP ticket includes 2 days all access, a catered buffet including an array of cannabis infused foods, live entertainment on a private stage in the tented VIP area, a celebrity meet and greet, vapor lounge, and 2 hash bars. A limited number of these tickets are being offered.  Over 50% of these have already been sold.   These tickets are only available at:  Angels Care in San Jose, Sonoma Patients Group in Santa Rosa, and 7 Stars in El Sobrante.  Judges will cast their ballot at the event and winners will be announced at 4:20pm on Sunday.

Up to date information and advance ticket sales are available at www.intcheevents.org.

Cured: A Cannabis Story (Video)

Cannabis Compound A Promising Treatment For Liver Fibrosis

Medical Marijuana Sign

he administration of the non-psychotropic cannabinoid CBD (cannabidiol) induces selective apoptosis in hepatic stellate cells (HSCs), according to preclinical findings reported in the journal Cell Death and Disease. The activation of HSCs is considered to be a key cellular event underlying hepatic fibrogenesis (excessive tissue build up), a condition that can result in liver failure.

Authors reported: “In this study, we find that CBD selectively kills activated HSCs. … We provide a molecular basis of action for CBD and identify CBD as a novel potential therapeutic agent for liver fibrosis.”

They concluded, “These promising findings warrant future investigation evaluating the anti-fibrotic effect of CBD in vivo. The prospect of CBD as a new anti-fibrotic compound is rendered more appealing by the fact that CBD is a non-psychoactive small drug-like molecule already approved for clinical use in many countries.”

Liver fibrosis is the tenth leading cause of death in the United States.

Norml

Previous studies have consistently reported that cannabinoids can selectively promote cell suicide in various malignant cell lines, including breast cancerlung cancer, and glioma.

For more information, please contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, “Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis,” appears in Cell Death and Disease.

OCD Can Be Treated With Medical Marijuana

Obsessive–compulsive disorder (OCD) is basically an anxiety disorder characterized by intrusive thoughts that produce apprehension, fear, uneasiness or worry by repetitive behaviors aimed at reducing the associated anxiety. Unnecessary repetition of activities such as washing, cleaning, and hoarding during the day or being preoccupied with thoughts of coitus, violence, and religious ideologies as well as disgust of specific numbers are the main hints of a person suffering from OCD.

Treatment

OCD is a treatable disease. With adequate therapy and correct counseling by experienced psychiatrist and physicians, the intensity of the disease can be decreased in little time. Effective treatments for obsessive-compulsive disorder are now easily available, and fresh researches are yielding new and improved therapies that can help people with OCD and other anxiety disorders lead productive, fulfilling lives.

Some doctors even say that Medical Marijuana (Cannabis) can also help in eliminating the disease. Dr. Breen of Southern California insisted that he has been successful in treating two patients with OCD via medical Marijuana. He shared, “Today I had two patients who have been successfully treating their symptoms of obsessive compulsive disorder with medical marijuana. One was a 46-year-old man whose symptoms are primarily having ‘to check things all the time.’ He explained having to walk back to his car all the time to check his door locks etc. The second was an 18-year-old male who had the compulsion to try and touch the ceiling in a room. In both cases their symptoms were disruptive to their daily lives.

Amazingly both had been using cannabis with god results to control their symptoms.”

Moreover, Dr. Bennett, a pediatric psychologist at New York-Presbyterian Hospital/Weill Cornell Medical Center, observed that OCD, in its earlier stages, is more easily removed than in its later stages. He maintained that children and adolescent suffering from OCD must be given more attention to help them get rid of the anxiety and stress of OCD.

“Anxiety is a normal part of growing up, but when it interferes with school, friendships or family life, we recommend parents seek treatment for their child. If a family is going to extreme measures to accommodate their child’s anxiety, or if their child has a problem with involuntary movements or vocalizations, we can offer help,” says Dr. Bennett.

Worth Repeating: Government Has Patent For Cannabinoids Since 2003

julius axelrod flip HHAABC.jpg
Photo: The Julius Axelrod Papers
Dr. Julius Axelrod, pictured above, conducted some of the original research which culminated in the United States government getting a patent on all cannabinoids in 2003.
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Welcome to Room 420, where your instructor is Mr. Ron Marczyk and your subjects are wellness, disease prevention, self actualization, and chillin’.

Worth Repeating
​By Ron Marczyk, R.N.
Health Education Teacher (Retired)

The United States federal government holds a “medical patent” for all cannabinoids — a patent which it has held since 2003.
Let’s take a look at the rationale behind this patent, and highlight the good news it actually contains for disease prevention, medical treatment and for cannabis legalization.
This patent was the outcome from research conducted by:
• Dr. Aiden J. Hampson, a neuropharmacologist at the National Institute for Mental Health (NIMH) in Bethesda, Maryland
• Dr. Julius Axelrod (1912-2004), Professor Emeritus, National Institutes of Health, pharmacologist and neuroscientist who shared the 1970 Nobel Prize in Physiology and Medicine
• Dr. Maurizio Grimaldi, professor of neurology/neuropsychopharmacology and toxicology, NIMH
Here’s how it all went down in 1998.

Patent No. U.S. 6,630,507 B1 (Source [PDF])
Assignee: The United States of America as represented by the Department of Health and Human Services (Washington, D.C.)
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Graphic: rm3.us

Patent Title: Cannabinoids act as antioxidants and neuroprotectants
Cannabinoids Patent Abstract.jpg

Field of the Invention (what it’s going to do)
The present invention concerns pharmaceutical compounds and compositions that are useful as tissue protectants, such as neuroprotectants and cardioprotectants. The compounds and compositions may be used, for example, in the treatment of acute ischemic neurological insults or chronic neurodegenerative diseases.
Definitions in this patent: Cannabinoid
“As used herein, a ‘cannabinoid’ is a chemical compound (such as cannabinol, THC or cannabidiol) that is found in the plant species Cannabis sativa (marijuana), and metabolites and synthetic analogues thereof that may or may not have psychoactive properties.”
Claims Found In Patent:
Claim #1: A method of treating diseases caused by oxidative stress, comprising administering a therapeutically effective amount of a cannabinoid to a subject who has a disease caused by oxidative stress.
Claim #15: A method of treating an ischemic or neurodegenerative disease in the central nervous system of a subject, comprising administering to the subject a therapeutically effective amount of a cannabinoid.
Claim #24: (A method of treating) wherein the ischemic or neurodegenerative disease is an ischemic infarct, Alzheimer’s disease, Parkinson’s disease, and human immunodeficiency virus dementia, Down’s syndrome, or heard disease.
If you read my last past, “Cannabis May Help Combat Aging of the Brain,” you’ll remember I presented current (2005-2009) evidence for cannabis and neuroprotection.
Well, apparently the U.S. government was way ahead of the curve on this one. Thank you, President Clinton, for filing this patent (April 29, 1999). Yo!
Maybe you didn’t inhale, but you may have legalized cannabis as a medicine through a back door during your presidency!
The “Assignee” on the patent is the United States of America. This means the people who are its citizens, who fund the government with their taxes, and are represented by it, and who in effect employ it to act as our agent protecting our welfare. The government works for us, and exists to serve us. We, the American people, are the ultimate owners of this patent that it holds for us.
In order to produce the maximum benefit for the most people, in the shortest time, we would like our patent to produce “fast tracked” cannabis-based medicines to treat the following medical conditions.
If you look at the chart below at the 10 o’clock position , “neuroprotection” is just the first benefit of this wonderful plant. We just scratched the surface of its full potential.
Cannabinoid Uses.jpg
Graphic: TRENDS In Pharmacological Sciences
Pharmacological actions of non-psychotropic cannabinoids (with the indication of the proposed mechanisms of action). Abbreviations: D 9 -THC, D 9 -tetrahydrocannabinol; D 8 -THC, D 8 -tetrahydrocannabinol; CBN, cannabinol; CBD, cannabidiol; D 9 -THCV, D 9 -tetrahydrocannabivarin; CBC, cannabichromene; CBG, cannabigerol; D 9 -THCA, D 9 -tetrahydrocannabinolic acid; CBDA, cannabidiolic acid; TRPV1, transient receptor potential vanilloid type 1; PPARg, peroxisome proliferator-activated receptor g; ROS, reactive oxygen species; 5-HT1A, 5-hydroxytryptamine receptor subtype 1A; FAAH, fatty acid amide hydrolase. (+), direct or indirect activation; “, increase; #, decrease.

And again, thank you for standing up for the people of this country first, not corporations. Thank you so much for looking out for our interests and securing the rights to this medicine so that it may be used by us, the American people.
That was eight years ago.
It makes one wonder what the U.​S. government was thinking when, this past March, it made the National Cancer Institute scrub its newly created cannabis web section to delete the phrase:
“In the practice of integrative oncology, the health care provider may recommend medical cannabis not only for symptom management but also for its possible direct anti-tumor effect.”
This, mind you, is after receiving a patent specifically on the point that cannabinoids are powerful anti-oxidative medicines that fight oxidative stress diseases. One of the main causes of cancer is oxidative stress disease.
“Many forms of cancer are thought to be the result of reactions between free radicals and DNA, resulting in mutations that can adversely affect the cell cycle and potentially lead to malignancy.”
Cancer patients need unrestricted access to cannabis products. The drug is self-regulating; if you use “too much,” you fall asleep.
This patent makes the case that cannabinoids should definitely be part of an integrative medical treatment plan for cancer and a multitude of other conditions as per the above statement.
All cannabinoids act as potent free-radical scavengers. Interesting fact: the patent claims that THC is equal to cannabidiol as an anti-oxidant in strength.
Only problem: it is “psychotoxic,” to use the patent’s terminology.
Translation: it gets you high.
Example of an Oxidative Disease
skin immediately after hydrogen peroxide.jpg
Skin immediately after exposure to 30 percent hydrogen peroxide

Hydrogen peroxide
‘s actions come from the fact that it oxidizes tissue.
This is how hydrogen peroxide gets that bloodstain out of your white shirt; it dissolves the cells by stealing electrons from proteins. Oxidation is to human DNA as rust is to an iron bridge, and as paint protects it from oxygen, cannabinoids are the “paint” that protect your DNA from destruction.
The cannabis plant originated in the mountains at high altitudes in Kurdistan. To protect itself from harmful ultraviolet radiation at in the thin air, the plant developed a chemical defense to protect itself. It evolutionarily selected for cannabinoids, antioxidants which counter this high intensity, less filtered form of sunlight radiation.
Now imagine this chemical reaction happening in your brain, just ripping apart neurons which are your individual brain cells. That is what neuroinflammation is. The good news is that cannabinoids shut down this reaction in the human body.
free radical damage to motor neurons.jpg

​Who would benefit from U.S. Patent #6,630,507 B1?

“Oxidative associated diseases include, without limitation, free radical associated diseases, such as ischemia, ischemic reperfusion injury, inflammatory diseases, systemic lupus erythematosis, myocardial ischemia or infarction, cerebrovascular accidents (such as thromboembolic or hermorrhagic stroke) that can lead to ischemia or an infarct in the brain, operative ischemia, traumatic hemorrhage (for example a hypovolemic stroke that can lead to CNS hypoxia or anoxia), spinal cord trauma, Down’s syndrome, Crohn’s disease, autoimmune diseases (e.g., rheumatoid arthritis or diabetes), cataract formation, uveitis, emphysema, gastric ulcers, oxygen toxicity, and neoplasia (cancer tumors).”
And radiation sickness, which I’m sure we will find in the Japanese population for years to come.
The government’s public mantra has always been that marijuana is not a medicine in any form, as in Schedule I, which means (a) the drug or other substance has a high potential for abuse; (b) it has no currently accepted medical use in treatment in the United States  (Remember U.S. Patent 6,630,507 B1?); and (c) there is a lack of accepted safety for use of the drug or other substance under medical supervision.
While spending billions of dollars to promote its anti-drug meme behind the scenes, it was simultaneously trying to prove to the Patent Office that cannabinoids are powerful anti-oxidative medicines that fight oxidative stress diseases in everyone.
So the crazy Catch 22 is that the U.S. government is now claiming cannabis is medicine, but is also saying it isn’t medicine and that it needs to be against the law.
How can any sane person explain this cognitive dissonance — this bipolar reefer insanity on the part of the government?
This patent contradicts the very definition of “Schedule I.”
And does the government’s patent also hold the cure for cancer and neurodegenerative diseases, and many other oxidative stress-related disorders?
Point to remember: this patent is making medical claims for cannabidiol only. THC is cannabidiol’s therapeutic partner, and they work together best in a synergistic fashion, which can be described as “cannabinergic.”
The patent acknowledges that all cannabinoids are therapeutic, but claims very high doses are needed to get the effect. This is an untested negative assumption about marijuana’s ability to change consciousness that has been an ideologically driven bias against cannabis since 1937.
This therapeutic dose would produce unwanted side effects if THC was used in this amount. The high from THC is described as “psychotoxic” in the patent. This is true if THC is not used with cannabidiol, as it is found in the whole plant.
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Dr. Julius Axelrod
​From U.S. Patent #6,630,507 B1:
“As referred to herein, the term ‘psychoactivity’ means ‘cannabinoid receptor mediated psychoactivity.’ Such effects include euphoria, lightheadedness, reduced motor coordination, and memory impairment. Psychoactivity is not meant to include non-cannabinoid receptor mediated effects such as the anxiolytic effect of CBD.”
Translation: Euphoria, literally, to “bear well,” is medically recognized as a positive mental, emotional state defined as a profound sense of well-being or wellness.
Lightheadedness, reduced motor coordination, and memory impairment, of course, can be bad. These last three apply to alcohol, high blood pressure meds, and many psychiatric meds in general.
Anxiolytic (anti-anxiety) is good.
Question: How does one separate “anxiety-free” from “experiencing joy and happiness”?
Why do we live in a Buzz-Kill Nation?
I have discovered that suffering and pain and very overrated, and don’t build character.
Did your last root canal surgery make you a better person? It only works if others in your peer group witness it and reward it within the group.
Pain and suffering damage the immune system.
Joy and happiness and giggling and laughing boost the immune response. When you laugh, your immune system laughs with you, and a laughing immune system is a good thing to have when you are fighting cancer or any serious illness.
Reduction of laughter frequency is a symptom of a diseased state.
Mirthful laughter has a positive effect on stress and natural killer cell activity.
From U.S. Patent #6,630,507 B1:
“THC is another of the cannabinoids that has been shown to be neuroprotective in cell cultures, but this protection was believed to be mediated by interaction at the cannabinoid receptor, and so would be accompanied by undesired psychotropic side effects.”
Here’s what happens when THC is used without its partner, cannabidiol.
Intravenous THC and Cannabidiol Experiment
What anti-marijuana researchers do is isolate and give pure THC only to test subjects, which in large amounts can cause psychosis-like symptoms. Then they claim marijuana causes psychotic behavior.
Both THC and cannabidiol are both equal in strength as antioxidants. But THC gets you high, which disqualifies it as medicine.
A medicine that makes you laugh is bad?
The patent made it sound like getting high — or should I say having a marijuana-induced “peak experience,” which leads in time to varying degrees of self-actualization — is a bad thing.
The “high” is therapeutic in its own right, being that cannabis is an entheogen drug and not an intoxicant. It can’t be included in the intoxicant category due to the fact that it is not toxic, and has never caused a recorded death directly from its use.
The change in consciousness induced by the THC/cannabidiol combo is anxiolytic, anti-depressive, and antipsychotic in nature. A cancer diagnosis with harsh chemo and radiation produces intense periods of anxiety and depression through the long course of treatment.
So let me get this part straight: the serious untoward side effects of cannabis are red eyes, lightheadedness, intense bouts of uncontrollable enlightened laughter, intense hunger followed by periods of deep mystical introspection, followed by deep sound sleep.
In short, happy, hungry and sleepy.
Cannabis is not an intoxicant. It is an entheogenic substance. Think altruism, group bonding and cooperation, nonviolence and sharing. Think Woodstock!
“Splendid by Law! Declaring Law, truth speaking, truthful in thy works, enouncing faith, King Soma! … O [Soma] Pavāmana, place me in that deathless, undecaying world wherein the light of heaven is set, and everlasting lustre shines … Make me immortal in that realm where happiness and transports, where joy and felicities combine.” ~ from the Rig Veda, the “Creator of the Gods.”
Cannabis is like yoga for your mind. But only different — and oh, the places you’ll go!
I believe if you live long enough, through many decades, absorbing the tragedies of the human condition, you have a high probability of developing a type of “generalized life PTSD.” It’s part of the psychological profile of aging, and it can’t be helped.
Life wears you down over time.
Cannabis is just a milder, non-toxic form of MDMA, which is helping some of our combat vets who return home with PTSD.
Many who are lucky enough to survive cancer go on to develop a “cancer PTSD” syndrome that will always be there.
So what are free radicals?
“Radicals (often referred to as free radicals) are atoms, molecules, or ions with unpaired electrons on an open shell configuration. Free radicals may have positive, negative, or zero charge. With some exceptions, the unpaired electrons cause radicals to be highly chemically reactive. Radicals, if allowed to run free in the body, are believed to be involved in degenerative diseases and cancers.
The antioxidants give an electron to the free radical so its outer shell is complete. If not, the free radicals degrade your DNA by plucking electrons from its structure. This damages the correct code for making new proteins that cells use to rebuild; this process is called “oxidation stress,” which means your cellular DNA is under attack by highly reactive chemicals.
What causes this oxidation?
• X-rays and all forms of radiation, even sunlight.
• Cancer treatment: chemotherapy, radiation treatment. From the patent: “The invention includes methods for using cannabinoids in subjects who have been exposed to oxidant inducing agents such as cancer chemotherapy, radiation, and other sources of oxidative stress.”
• Chemicals in our water and air that are toxic to cells. We live in a close bio-system; anything we dump down the drain winds up in the food chain, in the water we drink, and in the air we breathe.
It’s the sum total of every chemical and radiation assault against your DNA at the cellular level, inside the nucleus of your cells, that you don’t see. This damage causes mutations in cells that lead to abnormal cell growth and cancer.
normal oxygen atom.jpg
​This is why cannabinoids may slow the aging process.
This may be why cannabis smokers have a lower rate of lung cancer and head and neck cancer than the non-smoking population.
Cannabinoids protect the cells from oxidation. Marijuana saves lives!
Think of cannabis as a super free-radical-fighting vegetable. Get at least one serving of this green phytochemical per day to maintain good health!
Perhaps the FDA should consider adding cannabis to its new Food Pyramid. ☺
Thank you, Julius Axelrod (1912-2004), for all your hard work. Perhaps someone will name a medicine strain of cannabis for you.

Marijuana Compound Helps Treat HIV In Animal Testing

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Marijuana Pill Bottle

The long-term administration of delta-9-THC, the primary psychoactive compound in marijuana, is associated with decreased mortality in monkeys infected with the simian immunodeficiency virus (SIV), a primate model of HIV (human immunodeficiency virus) disease, according to in vivo experimental trial data published in the June issue of the journal AIDS Research and Human Retroviruses.

Investigators at the Louisiana State University Health Sciences Center assessed the impact of chronic intramuscular THC administration compared to placebo on immune and metabolic indicators of SIV disease during the initial six-month phase of infection.

Researchers reported, “Contrary to what we expected, … delta-9-THC treatment clearly did not increase disease progression, and indeed resulted in generalized attenuation of classic markers of SIV disease.” Authors also reported that THC administration was associated with “decreased early mortality from SIV infection” and “retention of body mass.”

marijuana medicine

Investigators concluded, “These results indicate that chronic delta-9-THC does not increase viral load or aggravate morbidity and may actually ameliorate SIV disease progression.”

Clinical trials have previously documented that the short-term inhalation of cannabis does not adversely impact viral loads in HIV patients, and may even improve immune function.

For more information, please contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, “Cannabinoid administration attenuates the progression of simian immunodeficiency virus,” is available online here:http://www.liebertonline.com/doi/pdf/10.1089/aid.2010.0218. Additional studies documenting the disease modifying potential of marijuana is available in the NORML handbook, Emerging Clinical Applications For Cannabis & Cannabinoids: Fourth Edition, available online at: http://norml.org/index.cfm?Group_ID=7002.

From Norml.org

Medical Marijuana And Cachexia

medical marijuana blog

You won’t have to research medical conditions treatable with medical marijuana for very long before you come across the term cachexia; if you’re not sure what this term means, you’re not alone so here we’ll explain exactly what cachexia is and how cannabis can help to alleviate it.

What is Cachexia?

This definition from the National Cancer Institute:

cachexia (ka-KEK-see-a)

Loss of body weight and muscle mass, and weakness that may occur in patients with cancer, AIDS, or other chronic diseases.

Cachexia invariably occurs with anorexia:

anorexia (a-nuh-REK-see-uh)

An abnormal loss of the appetite for food. Anorexia can be caused by cancer, AIDS, a mental disorder (i.e., anorexia nervosa), or other diseases.

What Causes Cachexia?

Although it depends very much on what type of cancer a patient has, it’s estimated that 50% to 80% of all cancer patients will develop cachexia, usually during the final stages of pancreatic, lung, and prostate cancers. The condition appears to result from the immune system’s response to the tumor.

Another major cause of cachexia is HIV/AIDS infection.

Cachexia Treatments

In most cases the standard for advanced cachexia is intravenous feeding, together with administration of an appetite stimulant drug – Megace. The problem with Megace is that the weight gain it stimulates is in the form of fat; the weight loss through the cachexia is lean tissue – muscles, heart tissue and the like.

dank nugget

Marijuana and Cachexia

Most people know about the way weed stimulates the appetite – the infamous munchies. The munchies is caused by the action of THC on the body and there have been a number of studies confirming that patients who use medical marijuana experience a reduction in rate of weight loss together with an increase in appetite. Sadly, research has also failed to show any advantage of taking THC and Megace in combination – they do not augment each other’s effects.

Chemotherapy Induced Nausea and Marijuana

It has been shown in various studies that, when used in the treatment of chemotherapy-induced nausea and vomiting, THC is more quickly absorbed from marijuana smoke than from any oral preparation. The only problem appears to be one of dose measurement; however, with experience, chemotherapy patients will learn to manage their weed dosage.

Courtesy of the Medical Marijuana Blog

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